| Adriamycin-Pfs IV
Doxorubicin is an anthracycline type of chemotherapy that is used alone or with other treatments/medications to treat several different types of cancer. Doxorubicin works by slowing or stopping the growth of cancer cells. How To Use Adriamycin-Pfs IV This medication is given by injection into a vein by a health care professional. Follow all instructions for proper mixing and dilution with the correct IV fluids. The final solution should be red. Before using, check this medication visually for particles. If particles are present, do not use the liquid. Before injecting each dose, clean the injection site with rubbing alcohol. .
ASCO and ASH Release Updated Guideline on the Use of Chemotherapy ...
WASHINGTON, Oct. 22 /PRNewswire-USNewswire/ -- Today, the American Society of Hematology (ASH) and the American Society of Clinical Oncology (ASCO) have released an updated joint guideline on the use of erythropoiesis-stimulating agents (ESAs), a class of drugs that stimulate the bone marrow to produce more red blood cells, to treat chemotherapy-related anemia. "One goal of these guidelines is to inform clinicians with the most up-to-date evidence from high-quality studies regarding the risks and benefits of ESAs in patients with cancer," said J. Douglas Rizzo, MD, MS, co-chair of the guideline panel and Associate Professor of Medicine, Medical College of Wisconsin. This updated guideline, originally published in 2002, was derived from systematic reviews and analysis of published clinical trials.
MicroRNA regulates cancer stem cells
One of the biggest stories in cancer research over the past few years has been, unexpectedly, stem cells. Not embryonic stem cells, but tumor stem cells. These mutated cells, which live indefinitely and can seed new tumors, are now suspected of causing many, if not all, cancers. What is worse, these persistent cells are not killed by chemotherapy or other current treatments. Their survival might explain why tumors frequently recur or spread after treatment. .
Drug study seeks those with advanced skin cancer
Seattle area patients with advanced skin cancer may have one more option in fighting the disease through a large study looking at an experimental drug for late-stage melanoma. Pacific Medical Centers of Seattle are recruiting patients into a large Phase 3 study to evaluate the drug Allovectin-7. The first two phases of the nationwide study showed the drug to be safe in patients, according to data presented in 2006 at the American Society of Clinical Oncology meeting. The current study compares whether the drug -- given as an injection to stimulate the immune system to destroy cancer cells -- works better than standard chemotherapy. About 375 patients in the U.S. will be enrolled in the trial. Patients whose melanoma is caught early often can be cured with surgery.
Study: Nanodiamonds deliver chemo drugs
EVANSTON, Ill., Oct. 15 A U.S. study suggests nanodiamonds are effective at delivering chemotherapy drugs to cells without the side effects seen with current drug delivery agents.
The Northwestern University study is said to be the first to demonstrate the use of nanodiamonds -- a new class of nanomaterials -- in biomedicine. In addition to delivering cancer drugs, researchers said the model could be used for other applications, such as fighting tuberculosis or viral infections.
Materials currently used for drug delivery can cause inflammation, a serious complication that can predispose a patient to cancer, block the activity of cancer drugs and promote tumor growth.
"There are a lot of materials that can deliver drugs well but we need to look at what happens after drug delivery," said Northwestern Assistant Professor Dean Ho, who led the study.
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